教授 吴燕

职称：教授、博导、“珞珈学者”特聘教授   专业：植物发育生物学   研究方向：植物细胞信号传导   实验室位置：生科院5107号   房间联系方式：Office Phone: (027）6875 3805　　　　　                         Lab Phone: 　 (027）6875 3832   Email: wuy@whu.edu.cn

教育经历：
学士， 1983，武汉大学生物系
硕士， 1986，武汉大学生物系
博士， 1991，武汉大学生物系

主要工作经历与任职：
2005－现在，教授，武汉大学生命科学学院。
2003－2005，资深研究员，TSRI （研究所），美国加州圣地亚哥。
2000－2003，科学家，Syngenta （公司），美国加州圣地亚哥。
1993－2000，博士后，美国洛克菲勒大学，美国纽约州纽约市。
1991－1993，访问学者，德国墨尼黑大学，德国墨尼黑市。

研究资助：
获得国家自然科学基金面上和重大研究计划项目、国家科技部973计划项目等的资助。

主要研究领域和兴趣：
1.研究植物激素脱落酸(ABA)信号传导途径的分子机理。探讨ABA与其它激素，如细胞分裂素和生长素在植物生长发育过程中所产生的互作调控关系。
2.研究ABA影响植物细胞骨架构架变化的细胞生物学机制。探讨植物在应答ABA的过程中细胞骨架的时空变化。
3.植物细胞DNA错配修复的生物化学机理的研究。

教学情况：
细胞生物学 （Cell Biology），春季授课，本科生国际班 (英文授课)。
细胞骨架与细胞运动，春季授课，研究生。
现代细胞学，春季授课，研究生。

代表性论文（*通讯作者）：

1. Zhao S., Wu Y., He Y., Wang Y., Xiao J., Li L., Wang Y., Chen X., Xiong W., and *Wu Y. (2015) RopGEF2 is involved in ABA-suppression of seed germination and post-germination growth of Arabidopsis. (2015) The Plant J. 84, 886-899.

2. Li L., He Y., Wang Y., Zhao S., Chen X., Ye T., Wu Y., and *Wu Y. (2015) Arabidopsis PLC2 is involved in auxin-modulated reproductive development. The Plant J. 84, 504-515.

3. Wang Y., Shen W., Chan Z., and *Wu Y. (2015) Endogenous cytokinin overproduction Endogenous cytokinin overproduction modulates ROS homeostasis and decreases salt stress resistance in Arabidopsis thaliana. Front. Plant Sci. 6:1004. doi: 10.3389/fpls.2015.01004

4. Wu Y., Zhao S., Tian H., He Y., Xiong W., Guo L. and * Wu Y. (2013) The CPK3 phosphorylated RhoGDI1 is essential in the development of Arabidopsis seedlings and leaf epidermal cells. J. Exp. Bot. 64, 3327-3338.

5. Wang Y., Li L., Ye T., Lu Y., Chen X., and * Wu Y. (2013) The inhibitory effect of ABA on flower transition is mediated by ABI5 in Arabidopsis. J. Exp. Bot. 64, 675-684.

6. Lu Y., Chen X., Wu Y., Wang Y., He Y., * Wu Y. (2013) Directly transforming PCR-amplified DNA fragments into plant cells is a versatile system that facilitates the transient expression assay. PLOS ONE 8, e57171.

7. Chen M.-L., Su X., Xiong W., Liu J.-F., Wu Y., Feng Y.-Q., Yuan B.-F. (2013) Assessing gibberellins oxidase activity by anion exchange/hydrophobic polymer monolithic capillary liquid chromatography-mass spectrometry. PLOS ONE 8, e69629.

8. Yao X., Xiong W., Ye T., and * Wu Y. (2012) Overexpression of the aspartic protease ASPG1 confers the drought avoidance in Arabidopsis. J. Exp. Bot. 63, 2579-2593.

9. Chen M.-L., Fu X.-M., Liu J.-Q., Ye T.-T., Hou S.-Y., Huang Y.-Q., Yuan B.-F., Wu Y., Feng Y.-Q. (2012) Highly sensitive and quantitative profiling of acidic phytohormones using derivatization approach coupled with nano-LC–ESI-Q-TOF-MS analysis. J. Chromatography B 905, 67-74.

10. Wang Y., Li L., Ye T., Zhao S., Liu Z., Feng Y.-Q. and  * Wu Y. (2011) Cytokinin antagonizes ABA suppression to seed germination of Arabidopsis by downregulating ABI5 expression. The Plant J. 68, 249-261.

11. Yao X., Horie T., Xue S., Leung H.-Y., Katsuhara M., Brodsky D.E., Wu Y. and Schroeder JI (2010) Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transporters in plant cells. Plant Physiol. 152, 341-355.

12. He Y.-Q., and * Wu Y. (2009) Oil body biogenesis during Brassica napus embryogenesis. J. of Integrative Plant Biology 51: 792-799.

13. * Wu Y. (2008) Guard Cells Signaling. (A Blackwell’s Annual Plant Reviews Series, Vol. 33, Intracellular Signaling in Plants, pp362-387. Editor, Dr. Zhenbiao Yang)

14. Wu Y., Sanchez J.P., Lopez-Molina L., Himmelbach A., Grill E., Chua N.-H. (2003) The abi1-1 mutation blocks ABA signaling downstream of cADPR action. The Plant J. 34, 307-315.

15. Wu Y., Wood M.D., Tao Y., and Katagiri F. (2003) Direct delivery of bacterial avirulence proteins into resistant Arabidopsis protoplasts leads to hypersensitive cell death. The Plant J. 33, 131-137.

16. Jin P., Wood M.D., Wu Y., Katagiri F. (2003) Cleavage of the Pseudomonas syringae type III effector AvrRpt2 requires a host factor(s) common among eukaryotes and is important for AvrRpt2 localization in the host cell. Plant Physiol. 133, 1072-1082.

17. Lemichez E., Wu Y., Sanchez J.P., Mettouchi A., Mathur J., Chua N.-H. (2001) Inactivation of AtRac1 by abscisic acid is essential for stomatal closure. Genes & Dev. 15, 1808-16.

18. Zuo J., Niu Q.-W., Nishizawa N., Wu Y., Kost B., Chua N.-H. (2000) KORRGIAN, an Arabidopsis endo-1,4-glucanse, localizes to the cell plate by polarized targeting and is essential for cytokinesis. The Plant Cell 12, 1-17.

19. Wu Y., Kuzma, J., Maréchal, E., Graeff, R., Lee, H.-C., Foster, R., Chua N.-H. (1997) Abscisic acid signaling through cyclic ADP-ribose in plants. Science 278, 2126-2130.

20. Wu Y., Hiratsuka K., Neuhaus G., and Chua N.-H. (1996) Calcium and cGMP target distinct phytochrome-responsive elements. The Plant J. 10, 1149-1154.

21. Aoyama T., Dong C.H., Wu Y., Carabelli M., Sessa G., Ruberti I., Morelli G., and Chua N.-H. (1995) Ectopic expression of the Arabidopsis transcriptional activator Athb-1 alters leaf fate in tobacco. The Plant Cell 7, 1773-1785.